Deramaxx tablets approved by the FDA as the first coxib class drug for veterinary use

Deramaxx tablets approved by the FDA as the first coxib class drug for veterinary use

Oct 01, 2002
By dvm360.com staff

Novartis Animal Health U.S., Inc. recently announced that the U.S. Food and Drug Administration (FDA) has approved Deramaxx chewable tablets, the first coxib-class drug to be approved for use in veterinary medicine. A coxib class drug is defined by the World Health Organization as a class of drug with a specific chemical structure that inhibits the COX-2 enzyme. "Coxib class drugs are 'smart medicines' that help the practitioner target the COX-2 enzyme primarily responsible for pain and inflammation in their patients, while sparing the COX-1 enzyme primarily responsible for normal platelet function, renal blood flow and gastric protection," says Jim Guidone, president and CEO, Novartis Animal Health U.S., Inc. "This product brings the latest in pharmacological research efforts to millions of dogs that are currently receiving traditional, less targeted medications to control their pain." Deramaxx is the only drug now approved for the control of pain and inflammation associated with orthopedic surgery in dogs. "The introduction of Deramaxx tablets is a significant advance in helping to address practitioner concerns about the treatment of post-surgical pain and inflammation in dogs," says Dr. Ralph Claxton, manager, new product development. "Just as advances are being made in human medicine, Novartis Animal Health is dedicated to bringing those next generation of pain control options to veterinary medicine." Deramaxx has passed extensive safety and efficacy studies required by the FDA. Multiple studies proved a statistical difference in pain control over placebo. As with all drugs, side effects may occur. These are normally mild, but may be serious. In a field study, the most common side effects were gastrointestinal signs or incision leakage. Dogs should be evaluated for pre-existing medical conditions before beginning any new medication and monitored during therapy. Refer to full product labeling for more information. Deramaxx tablets are available in 25mg and 100mg tablets and are beefy-flavored for easy oral administration. Tablets can be given once-a-day for 24-hour control of pain and inflammation and may be given with or without food.

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