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Regional nerve blocks key to delivering quality dental care


Brett Beckman
The use of regional nerve blocks for oral surgery in dogs and cats is synonymous with quality patient care.

This article details techniques that can be incorporated into companion-animal-hospital dentistry service to maximize safety, care and comfort for patients undergoing oral surgical procedures.

This discussion suggests adopting less misleading names for the regional nerve blocks, relying on simple anatomical regions blocked rather than traditional confusing nomenclature.

Detailed descriptions of regional and local nerve blocks commonly used to provide analgesia for oral surgery in veterinary patients have appeared in numerous publications.

Complete analgesia to the targeted tissue and a reduction in the concentration of the inhalant anesthetic are two significant benefits of proper administration of local agents. Hypotension, bradycardia and hypoventilation are complications that can be minimized by the use of local and regional blocks for oral surgery. Local blocks eliminate the perception of pain, making surgical anesthetic depths unnecessary.


This author commonly uses lidocaine and bupivicaine combined in the same syringe for regional oral-nerve blocks. Lidocaine is not desirable as a sole agent due to its limited effect post administration (one to two hours). Bupivicaine requires administration much earlier in the anesthetic event than lidocaine in order to be effective prior to surgical tissue manipulation. These limitations can be minimized or eliminated by using them in combination. The quick onset of lidocaine, coupled with bupivicaine's extended duration of effect (up to eight hours), make them a good choice for combined use in regional nerve blocks. The agents may be used with or without epinephrine.

Although rare, complications are possible with inadvertent systemic administration or systemic uptake of locally delivered local-anesthetic agents. Central nervous system excitement, including seizures, followed by depression, apnea, severe cardiovascular compromise, dysrhythmias and hypotension are all possible. Direct toxicity to skeletal muscle and anaphylactic reactions are possible with local administration. The author has never experienced any of these complications at the doses recommended in this article.

Dosing considerations

Table 1: Recommended infusion volumes
A maximum dose of 1.0 mg/kg of each agent in combination in the same syringe is recommended. Care should be exercised, especially in smaller patients and cats, so that maximum doses are not exceeded. The ratio of lidocaine: bupivicaine is 1:4 when using concentrations of 2 percent and 0.5 percent, respectively. The total volume used depends on the size of the patient and the number of sites that require analgesia. The maximum number of sites would be four if the patient requires surgical manipulation in all four quadrants.

Table 2: Sample calculation for regional nerve block for oral surgery in a small patient
Table 1 shows recommended infusion volumes per site based on patient size. Please note that these volumes represent both agents mixed together. Table 2 shows a sample calculation for a 4-kg dog.

Table 3: Sample calculation for regional nerve block for oral surgery in a large patient
Physiologic parameters will determine if the block is effective. If blood pressure, heart rate and respiration rate increase with surgical manipulation, the block either was not correctly placed or hasn't had the proper amount of time for onset (five minutes). If enough time has elapsed and the attending veterinarian believes the time for onset is not an issue, then the block may be repeated as long as the maximum total dose is not exceeded. It should be noted that the low ph of inflamed tissue will render local anesthetics less effective.


Based on human research, the use of local analgesics and opiates in combination provides extended duration of action. The addition of morphine or buprenorphine to a regional brachial plexus block for limb amputation demonstrated close to a twofold increase in duration of effect over patients receiving only bupivicaine in one study. A similar model was used in another study where researchers demonstrated that the addition of buprenorphine to the regional block provided significant increases in duration compared to giving the buprenorphine intramuscularly.

The author currently uses opiates in the lidocaine/bupivicaine mixture for procedures where increased duration of effect are desirable. Patients that are particularly difficult to medicate, either in the hospital or at home, may benefit from this combination.

Chronic pain states, as seen in canine or feline stomatitis, may make post-operative pain management challenging. Morphine may be used as a portion of the premedication protocol at 0.5 mg/kg IM 20 minutes prior to induction. One-fourth of that same volume is added to the local mixture per site to be blocked. Hydromorphone is administered at 0.1 mg/kg as a portion of the premedication protocol. One-fourth of that same volume is added to the local mixture per site to be blocked. Buprenorphine may be used as a premedication at 0.015 mg/kg following the same volume recommendations for local infiltration as with the examples above.

Morphine and hydromorphone are pure mu agonists and are preferred for management of severe pain. Buprenorphine, a partial mu agonist, is a good choice for mild to moderate pain. All three agents may be used in either species, but pure mu agonists, in particular hydromorphone, are known to cause hyperthermia in cats. If pure mu agonists are used either locally or systemically in cats, temperature should be monitored during and up to five hours post procedure.


None of the regional nerve blocks for oral surgery in dogs and cats need any special equipment to employ. A tuberculin syringe with a 5/8-in., 25-gauge needle is used for patients 4 kg or less. Three-or 6-ml syringes with 22-25 gauge, 3/4-in. needles are used for patients more than 4 kg, depending upon the volume to be infused. The correct dose of the desired agents is drawn. The needle is advanced to the desired location. Aspiration is performed to ensure the needle is not in a vessel and the agent is dispersed. If one encounters a vessel, the needle is redirected and aspiration repeated. Once extravascular placement is confirmed, the agent is administered. Be careful not to advance the needle during injection to avoid inadvertent vessel penetration.

Directional terms

Photo 1: Mesial and distal are locational terms used to describe proximity to a certain tooth. In this example, the arrows are pointing to regions both mesial and distal to the mandibular left third premolar.
An introduction of two important directional terms is indicated prior to our discussion of the individual nerve blocks. These two terms are used when describing direction adjacent to an individual tooth (Photo 1). The first term is mesial. It describes the area adjacent to a particular tooth that is toward the maxillary or mandibular midline (where the incisors of the right and left arcades meet). A similar, more familiar, term is rostral. It refers to direction in a larger context, considering the skull in general rather than an individual tooth. Distal is the term used to describe the area adjacent to a tooth away from the midline. Caudal is a similar less-descriptive term.


Source: DVM360 MAGAZINE,
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